• The need for dedicated DAPT updates is

  2019-07-15

  

  The need for dedicated DAPT updates is well justified by the large amount of data and new information generated in the field over the past few years. As expected, the ACC/AHA and ESC updates contain large areas of overlap as well as some differences. Differences were largely explained by the differe

• ERR is present early in

  2019-07-15

  

  ERRβ is present early in the developing placenta in a subset of Senegenin in extra-embryonic ectoderm destined to make up the chorion.19, 20 ERRβ is likely essential for reproduction. ERRβ expression is essential for the maintenance of pluripotency and self-renewal potential in mouse embryonic stem

• In normal chow fed mice EP deficiency also

  2019-07-15

  

  In normal chow fed mice, EP4 deficiency also decreased the expression of CYP8B1, the downstream target of CYP7A1. Similarly, knockdown of EP4 with small interfering RNA reduced the expression of CYP8B1 in HepG2 cells. Therefore, it was anticipated that there would be an increased expression of CYP8B

• The four other mutations S T V I

  2019-07-13

  The four other mutations (S281T, V317I, T328A and A329S) were not detected in the absence of the A286S.

• Molecular modelling studies were performed on the hDHFR inhi

  2019-07-12

  Molecular modelling studies were performed on the hDHFR inhibitors identified (1, 11, 13, 14, 16, 25 and 32) to explore the structural basis of the interaction between the mentioned compounds and the human enzyme.

• Author Contributions Acknowledgments Introduction Many ant

  2019-07-11

  Author Contributions Acknowledgments Introduction Many anticancer agents bind covalently to DNA, introduce bulky adducts, and inhibit DNA metabolic processes including repair, replication and transcription.1., 2., 3.

• Introduction Biocatalysis can be used to synthesize chiral

  2019-07-10

  Introduction Biocatalysis can be used to synthesize chiral building blocks, such as monomers for polymer materials, and precursors for pharmaceuticals [[1], [2], [3], [4]].

• Anaesthetized mice of one eNOS

  2019-07-09

  Anaesthetized mice of one eNOS-KO strain showed a paradoxical decrease in blood pressure (BP) in response to i.p. administration of the NOS-inhibitor L-NA suggesting a role for non-endothelial isoforms of NOS in maintaining BP [1].

• Introduction Phosphorus P is an important nutrient for plant

  2019-07-08

  Introduction Phosphorus (P) is an important nutrient for plant growth; however, in many regions of the world soils are low in plant-available P (Holford, 1997).

• An increased CK activity was found in septal

  2019-07-05

  An increased CK2 activity was found in septal neuronal surface antigen (208-215) [Hepatitis B Virus] dissected from rat embryos after hypoglycemia [36].

• HEK cells stably transfected with CysLT were stimulated with

  2019-07-04

  HEK-293 transferrin fragment stably transfected with CysLT1 were stimulated with LTD and internalization was studied by confocal microscopy, FACS or cell-surface ELISA.

• The key difference between the membrane zymography

  2019-07-03

  The key difference between the membrane zymography and classical measurements of enzyme activities in soil slurries is the enzyme-substrate accessibility.

• The EGFR belongs to the ErbB family of

  2019-07-02

  The EGFR belongs to the ErbB family of receptor tyrosine kinases (RTKs), comprised of four members: EGFR (ErbB1, HER1), HER2 (ErbB2), HER3 (ErbB3) and HER4 (ErbB4) [24].

• A summary of the drug CDK hydrophobic hydrogen bonding

  2019-07-01

  A summary of the drug-CDK2/6/9 hydrophobic (Φ), hydrogen-bonding (H), and polar-bonding (P) interactions based upon the KLIFS residue numbers is provided in Table 5.

• Es en virtud de estas afirmaciones

  2019-06-29

  Es en virtud de estas afirmaciones que propongo retomar una perspectiva literaria para pensar los modos diversos de concebir la representación, así como atender GnRH Associated Peptide (GAP) (1-13), human la insistencia con que se acude a “lo real” (e incluso al “realismo”) para caracterizar las crónicas de la conquista en general y la de Bernal Díaz en particular.

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