• br Introduction Lycium barbarum also known as

  2021-01-15

  

  Introduction Lycium barbarum, also known as wolfberry, belongs to the plant family Solanaceae. Red-coloured fruits of L. barbarum are used as traditional Chinese herbal medicine to promote health and longevity and as a food supplement for thousands of years [1]. They possess many biological activ

• br Endothelial mechanotransduction br Apoptosis br Death ass

  2021-01-15

  

  Endothelial mechanotransduction Apoptosis Death associated protein kinase Conclusion DAPK is localized to the Eribulin mesylate network, and promotes actomyosin contractility. DAPK stabilizes stress fibers by phosphorylation of MLC (Bialik et al., 2004, Kuo et al., 2003). In endothelial

• Furthermore we found that expression of two

  2021-01-15

  

  Furthermore we found that expression of two C1 nodule cysteine proteases, Glyma.06G283100 and Glyma.06G174800, changed very little under drought despite the two proteases having similarity to the Arabidopsis senescence-related SAG12 gene with 62% similarity by Glyma.06G283010 and 58% by Glyma.06G174

• Moreover the imbalance between pro and anti inflammatory cyt

  2021-01-15

  

  Moreover, the imbalance between pro and anti-inflammatory cytokine production is present in various types of diseases. The use of substances able to induce anti-inflammatory cytokines could represent an important advance in the therapeutic treatment of a range of diseases. In this context, medicinal

• The aim of the present study

  2021-01-15

  

  The aim of the present study was to investigate the participation of CRF1 and CRF2 in the alterations of the dorsal and ventral striatal dopamine release and the vertical and horizontal locomotor activity observed in rats following chronic nicotine treatment and consequent acute withdrawal. In this

• We found that E and GEN each has mostly

  2021-01-15

  

  We found that E2 and GEN each has mostly similar effects on recruitment of the epigenetic modulators to the MB-COMT distal promoter (summarized in Table 2). These effects are associated with increased promoter methylation and gene suppression of COMT. It is noted that the array of epigenetic modulat

• br Introduction Myotonic dystrophy dystrophia myotonica DM i

  2021-01-15

  

  Introduction Myotonic dystrophy (dystrophia myotonica, DM) is an autosomal dominant disorder and the most common form of inherited muscular dystrophy in adults [1]. DM is characterised by a wide range of symptoms, including myotonia, progressive muscle loss, cataracts, cardiac conduction defects,

• br Effects of estrogens on

  2021-01-15

  

  Effects of estrogens on bone Estrogens play an important role in bone remodeling, as demonstrated by studies in mice in which the ER genes were deleted [21], [22]. ERβ compensates for the bapta am of ERα, and vice versa, but when both ERs are deleted a profound decrease in trabecular bone volume

• Current therapeutic protocols in OS and ES consist

  2021-01-14

  

  Current therapeutic protocols in OS and ES consist of neoadjuvant chemotherapy and local surgical resection, followed by adjuvant chemotherapy. These treatments lead to a 70% overall survival for localized disease but can decrease to 15% in case of metastasis. With CS being resistant to conventional

• Yu et al also reported that

  2021-01-14

  

  Yu et al. [24] also reported that extracting consortium of hydrolytic enzymes from sludge flocs performs better than costly single purified commercial enzyme. Thus, it is concluded from the above cited literature analysis that only few studies have been reported on extraction of enzymes from waste s

• Oxysterols modulate the immune responses and as

  2021-01-14

  

  Oxysterols modulate the immune responses and as such could be effectors of the tumor environment: 25-OHC impairs IgA production in B-lymphocytes [26] and induces the secretion of the proinflammatory and angiogenic cytokine IL-8 [27], [28]. Of note, oxysterols (in particular 7α,25-OHC) are potent che

• In contrast to SQLE HMGCR could be efficiently degraded in

  2021-01-14

  

  In contrast to SQLE, HMGCR could be efficiently degraded in IL-4, murine recombinant receptor lacking UBE2J2. However, this was not the case in cells devoid of UBE2G2, as these cells were unable to support 25-hydroxycholesterol (25-HC)-stimulated degradation of HMGCR (Fig. 1C). This finding is cons

• br DDR role in kidney Thirty eight

  2021-01-14

  

  DDR1 role in kidney Thirty-eight papers are reported in PubMed upon the keyword search “DDR1 AND kidney”. Careful examination of those papers shows that only 31 are related to DDR1's role in glomerulosclerosis and renal fibrosis, 24 of those being research and the rest review articles. Since the

• Therefore in this study we determined

  2021-01-14

  

  Therefore, in this study we determined whether exogenous LTD, a potent agonist of both CysLT and CysLT receptors , , induces Calcium Ionophore I australia edema and AQP4 expression in mouse brain; if so, which subtype of the receptors is involved in AQP4 expression in mouse brain and the cultured ra

• br Conflicts of interest br Acknowledgments Work in the

  2021-01-14

  

  Conflicts of interest Acknowledgments Work in the laboratory of SPS is funded by Council of Scientific and Industrial Research (CSIR) Network Project BSC-0111 (INDEPTH) and BSC-0112 (NanoSHE). We are thankful to Director, CSIR-IITR for his constant encouragement and support. We also acknowledg

14396 records 682/960 page Previous Next First page 上5页 681682683684685 下5页 Last page